Resumen
Background: Although significant progress has been made in the rights of the LGBTQ+ community, even today
this population still faces stigma and discrimination that impacts their mental health. In the case of men who
have sex with men, it has been demonstrated that the use of drugs in a sexual context (chemsex) is one of the
coping mechanisms and means of escape to deal with these situations. Method: We assessed 284 native Spanish speakers’ participants, 45,4 % were not engaged in sexualised drug use (n = 129) while 54,6 % were chemsex users (n = 155) using 18,7 % of them the injected via. The participants
completed six questionnaires about life and sexual satisfaction, depression, anxiety, internalised homophobia
and personality. Bivariate and multivariable logistic regression were performed to assess the associations be-
tween sexual behaviour-related and psychological variables. Kruskal-Wallis H test was used to analysed the
impact on mental health of the administration via.
Results: Aged, unprotected sexual relationships, positive serostatus, homonegativity and conscientiousness pre-
dicted the chemsex engagement. Furthermore, we found differences regarding the administration via.
Conclusions: We conclude that mental health significantly correlates with the practice of chemsex, highlighting
the importance of integrating mental health considerations into the prevention of risky sexual behaviors.